Cart
sales@molnova.com
Home - Products - Others - Other Targets - Jatrorrhizine chloride

Jatrorrhizine chloride

CAS No. 6681-15-8

Jatrorrhizine chloride ( Neprotine chloride;Yatrorhizine chloride )

Catalog No. M21537 CAS No. 6681-15-8

Jatrorrhizine chloride is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 hippocampal neurons.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 In Stock
10MG 58 In Stock
25MG 104 In Stock
50MG 160 In Stock
100MG 241 In Stock
500MG 498 In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Jatrorrhizine chloride
  • Note
    Research use only not for human use.
  • Brief Description
    Jatrorrhizine chloride is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 hippocampal neurons.
  • Description
    Jatrorrhizine chloride is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 hippocampal neurons.
  • Synonyms
    Neprotine chloride;Yatrorhizine chloride
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    OCT; PMAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6681-15-8
  • Formula Weight
    373.8
  • Molecular Formula
    C20H20ClNO4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:5 mg/mL (13.38 mM)
  • SMILES
    COc(ccc1cc(-c(cc2OC)c(CC3)cc2O)[n+]3cc11)c1OC.[Cl-]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sun S et al. Jatrorrhizine reduces 5-HT and NE uptake via inhibition of uptake-2 transporters and produces antidepressant-like action in mice. Xenobiotica. 2019 Oct;49(10):1237-1243.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Podecdysone B

    Podecdysone B is a natural product(phytoecdysone) isolated from Cyanotis arachnoidea.

  • (S)-(+)-Carvone

    (S)-(+)-Carvone is the main constituent of caraway oil and pineapple seed oil.

  • 4-Quinolinecarboxyli...

    4-Quinolinecarboxylic acid showed anti-tumor activity against L1210 leukemia and B16 melanoma.

Sign In Join Free